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EC number: 442-390-9
CAS number: 40573-09-9
Water solubility of MV 31 is determined to be 145 ug/L at 23 °C.
The water solubility of MV 31 was measured in 2013 according to US EPA
OPPTS 830.7840 (Water Solubility) test guideline and was conducted under
GLP. Triplicate samples were incubated for 4, 5, and 6 days at
approximately 30 °C. Samples were equilibrated at room temperature ( ~
23 °C) for at least 24 hours prior to analysis. MV 31 has a measured
water solubility of 145 ug/L at approximately 23˚C, as an average of day
4, 5, and 6 measurements. The overall %RSD was 9.5%. This is a guideline
study conducted under GLP compliance with no deviation. Therefore, it is
considered reliable without restrictions and a key study.
A previous study conducted in 2002 following EU Method A.6 (Water
Solubility) flask method and conducted under GLP compliance resulted in
the water solubility of MV 31 ≤ 20 mg/L at 20 °C. Although the measured
value was lower than the detection limit and test system had poor
recoveries for calibration standard recheck and matrix spikes, it is in
agreement with the conclusion that MV 31 is slightly soluble (0.1-100
mg/L) in water. Therefore, it is considered as a supporting study.
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