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EC number: 442-390-9
CAS number: 40573-09-9
The mutagenic potential of the test article was evaluated in the
Bacterial Reverse Mutation Assay with S. typhimurium strains TA98,
TA100, TA102, TA1535, and TA1537 in the presence and absence of a
metabolic activation system (Aroclor induced-S9 mix). The study was
performed in compliance with OECD GLP (1999). The test method was based
on OECD No. 471 (1997), U.S. EPA: OPPTS 870.5100 (1998), and EC
Directive 2000/32/EC B.13/B.14. All strains were exposed to dose levels
of 50, 160, 500, 1600, or 5000 ug per plate by incorporation of the test
article into the agar. Strain specific experiments were performed in the
presence and absence of metabolic activation. Plates were incubated for
48 hours at 37 C in the dark. After incubation, revertant colonies were
counted. No mutagenic responses were observed in any strain in the
presence or absence of metabolic activation. Based on the results of the
test, the test article is not mutagenic with or without metabolic
activation in the Ames assay.
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