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EC number: 251-718-8
CAS number: 33885-52-8
was performed to assess the bioconcentration of Pinyl Isobutyraldehyde
in Cyprinus carpiounder flow through conditions. The test material in
this test is 50% the aldehyde type (the registered material) and half
the acetal version of this aldehyde, with two additional C-atoms. The
focus in this summary will be on the aldehyde constituent and its
primary degradation product, the alcohol.The
study was conducted in accordance withJapanese
guidelinesand GLP principles
equivalent to OECD TG 305. A solvent was used due to the limited
solubility of the substance.During the
uptake phase, groups of 28 carp were exposed for 28 days to two
concentrations of test substance dispersed with N-N-dimethylformamide
and 14 fish exposed to untreated control. Nominal test concentrations of
1 and 10µg/Lwere
used and based on an acute toxicity test using Oryzias latipes(rice
fish). Concentrations of
the test item in water were maintained >= 86% of the nominal concentrations and
the variations were within ±20% of the average measured concentrations.The
lipid content of the fish (as mg/kg wet weight) at the end of the
experiment did not differ from that at the start by more ± 25%.The
BCF values for the Aldehyde constituent (the registered substance) was <
27 l/kg. Itsmetabolite
being the alcohol derivative:α,α,6,6-tetramethyl-bicyclo[3.1.1
]hept-2-ene-2-propanol, showed a BCF of 32.Overall
Pinyl isobutyraldehyde as the registered substance has no
bioaccumulation potential (BCF < 100 l/kg).
(For completeness: the
BCF values of Acetal constituent was roughly 300 and 400 at
concentrations of 1 and 10 µg/L, respectively, which were reached within
Value is '< ' , i.e. < 27 L/kg ww.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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