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EC number: 251-718-8
CAS number: 33885-52-8
Floralozone was tested in an acute dermal toxicity study similar to OECD
TG 402 under GLP. Ten New Zealand White rabbits were exposed to the test
substance via dermal application. Six males and four females were
exposed to 5000 mg/kg bw. After an observation period of 14 days animals
were necropsied. All animals survived the study in generally good
health. Changes in body weights were generally normal. Internal organs,
on superficial examination, appeared normal. Skin reactions were
generally slight on days 1 and 7 and generally cleared by day 14. One
animal had severe edema on day 1 and crusted skin at necropsy on day 14.
Scaly skin was observed in 6 out of 10 animals at necropsy. The LD50 was
determined to be higher than 5000 mg/kg bw.
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