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EC number: 259-134-5
CAS number: 54381-16-7
purpose of this in-vivo skin irritation test was to evaluate skin
irritation potential of N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine
Sulfate when applied to rabbit’s shaved intact and abraded skin.
rabbits (4 female and 2 male) were used in each treatment group (shaved
intact and abraded skin). 500 mg of test substance was applied to the
test site of each rabbit.
treated skin site was observed for edema and erythema for 24 h and 72 h
signs of irritation were observed in any of the treated animals (shaved
intact and abraded skin) during the study period.
on above, application of undiluted
N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate to rabbit’s shaved
intact and abraded skin did not produce skin irritation. The test
substance was classified as a non-irritant to rabbit skin.
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