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EC number: 218-414-7
CAS number: 2146-71-6
The bacterial reverse mutation assay (Ames Test) according to OECD 471
did not produce any positive results with the test substance Vinyl
laurate in tester
strains TA 98, TA 100, TA 1535 and TA 1537 both with and without
metabolic activation up to concentrations of 5000 µg/l. Concentrations
of 25, 50, 250, 500, 2500 and 5000 µg/plate were tested based on a dose
range finding test. The substance was soluted in dimethyl sulphoxide and
was administered via plate incorporation. No precipitation was seen
whereas phase separation occured in the highest dose tested because of
virtually insolubility of the test substance in water. Signs of toxicity
were seen in the highest tested concentration of 500 µg/plate for tester
strain TA 98 both with and without metabolic activation. The negative,
solvent and positive controls worked as expected.
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