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EC number: 218-414-7
CAS number: 2146-71-6
A group of five male and five female Wistar rats was treated with
Vinyl laurate at 2000 mg/kg by single dermal application according to
OECD Guideline 402 with a 14 days observation period. One animal died
during the first day after application. Only slight signs of toxicity
were not observed in the surviving animals like flat/hunched posture,
piloerection Diarrhea, chromodacryorrhoea (snout) and/or ptosis. The
animals recovered from the symptoms between day 2 and 4 of the study.
Scales and scrabs were seen in the treated skin area of several
animals during the observation period. The body weight of the animals
was within the range of physiological variability known for rats of
this strain and age. No macroscopic findings were observed at necropsy
of the animals. The LD50 (dermal, rat) was determined to be > 2000
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