Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-677-5
CAS number: 124-07-2
Table 1: Mortality [%] of fish
Incubation time [h]
2 - 5
solvent control (Tween 80)
320 (pH adjusted)
560 (pH adjusted)
* Fish showed decreased swimming ability
The results indicate, that at least part of
the toxicity of the test substance can be explained by its pH-lowering
Table 1: Mortality and sublethal effects of
the test substance to fish
Time after test start [h]
Nominal test concentrations [mg a.s./L]
m = mortality [%]
r = all fish were respiring rapidly
l = all fish were lethargic
s = all fish were at the test
f = fine white flocculent was observed
in the test solution
c = test solution was cloudy
* not all, but 2 fish were lethargic
Table 3: Mortality of fish at different test
substance concentrations [%]
0 mg/L (control)
LC50 (96 h) = 22 mg/L (nominal), based on mortality of Lepomis macrochirus
In the key study (1982) the toxicity to Lepomis macrochirus was
tested under static conditions according to an EPA-method (1975, Methods
for acute toxicity tests with fish macroinvertebrates, and amphibians).
Nominal test concentrations were 3.1, 5.2, 8.6, 14, 24 and 40 mg/ L. No
analytical monitoring was performed. At all concentrations all fish
respired rapidly and the test solution was cloudy. In addition at the
three highest concentrations, all fish were lethargic. After incubation
time of 96 h, an LC50 of 22 mg/L (nominal) was determined.
The observation of toxic effects in the range of water solubility
was corroborated by further test results.
In a supporting study (1977) according to a bioassay practice from
U.S. EPA (1975), Lepomis macrochirus as the test organism was exposed to
10, 18, 32, 56 and 100 mg/L test substance. The study resulted in an
LC50 (96 h) of 39.9 mg/L.
In a further supporting study (2002) conducted according to DIN
38412/15, Leuciscus idus was exposed to 100, 300, 1000, 3000, 10000 mg/L
test item. The study showed effects towards the fish species, resulting
in an LC50 (48 h) of 170 mg/L.
In a static study conducted for 48 h (Onitsuka 1989, no guideline
followed) in freshwater and in saltwater medium with Oryzias latipes as
the test organism, an LC50 of 57 mg/L for freshwater and an LC50 of 150
mg/L for saltwater was determined. Allthough the publication gives
valuable information the
documentation is inadequate for assessment purposes and the study was
rated as RL4.
The last available study (1988), reported an LC50 of 134 mg/L.
However, due to significant methodological deficiencies this study was
considered not reliable and rated RL 3.
In conclusion, octanoic acid shows toxicity to fish within the
range of water solubility, with an LC50 of 22 mg/L being the most
sensitive value. This value was therefore used for further assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again