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EC number: 204-677-5
CAS number: 124-07-2
Studies on the acute toxicity of octanoic acid to freshwater
species of three trophic levels (fish, invertebrates and algae) and
microorganisms are available. Long-term data for fish and aquatic
invertebrates were not available and therefore in accordance to
Regulation (EC) No 1907/2006 Annex XI, 1.5 a read across was conducted
to the structurally related sodium laurate (CAS 629-25-4) and decanoic
acid (CAS 334-48-5), respectively. Furthermore, good quality read across
data from decanoic acid (CAS 334 -48 -5) are used to assess the
short-term toxicity of octanoic acid to aquatic invertebrates.
Based on the key studies fish were the most sensitive organism to
octanoic acid in acute toxicity tests, with an LC50 (96 h) of 22 mg/L
(mortality). Test with aquatic invertebrates resulted in an EC50 (48 h)
of > 21 mg/L (meas. geom. mean) while an ErC50 (72 h) of 43.73 mg/L
(meas.) was reported for aquatic algae.
Comparing the long-term results of the three trophic levels,
aquatic invertebrates are considered to be the most sensitive aquatic
organisms with a NOEC (21 d) of 0.2 mg/L (nominal).
Microorganisms are not sensitive to octanoic acid. This assumption
is based on an EC10 of 912 mg/L determined in a study conducted with
Pseudomonas putida as the test organism.
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