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EC number: 204-677-5
CAS number: 124-07-2
The data set for the category member Fatty Acids regards
biodegradation includes standard biodegradation studies as well as data
obtained by QSAR. As summarized in the category justification, the
members of the fatty acid category demonstrate ready biodegradability.
The vast majority of the experimental results revealed ready
biodegradability, which was supported by reliable QSAR predictions. In
some cases insufficient sampling points were available to determine
whether or not the 10-day window was met. Studies in which the 10-day
window was not met likely did not ensure that the fatty acids tested
were fully in solution. According to the ECHAs Guidance on information
requirements and chemical safety assessment (Chapter R.7b: Endpoint
specific guidance, 2008) the screening tests on ready biodegradation
sometimes fail because of the stringent test conditions, in general, and
the differences among the individual tests in terms of their stringency.
Therefore, consistent positive test results should generally supersede
negative results. In conclusion, aliphatic fatty acids comprising C6-C22
carbon chain length are considered to be readily biodegradable. This
judgment is consistent with the hazard assessment presented in the OECD
SIDS (2009) for the category “Aliphatic Acids Category” where aliphatic
fatty acids with a carbon chain length in the range of C6 – C22 also
were assessed to be readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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