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EC number: 229-194-7
CAS number: 6425-39-4
Criteria for a valid test:
All criteria for a valid test were met because of the following:
- The incidence of micronucleated polychromatic erythrocytes in the
vehicle control groups did not exceed the historical vehicle control
- The incidence of micronucleated polychromatic erythrocytes in the male
and female positive control groups was significantly increased relative
to the respective vehicle control groups (p < or = 0.05, binomial
distribution, Kastenbaum-Bowman Tables).
However, the results of the statistical analysis would not be the only
criteria in determination of the test substance positivity. A
dose-dependent increase or biological relevance of the data would have
been taken in consideration. In addition, if criteria for either a
positive or negative genotoxic response were not met, the results would
have been judged as equivocal.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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