2,2'-dimorpholinyldiethyl ether

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1996-02-16 to 1996-03-08

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

Well documented non GLP study performed according to OECD Guideline 117 (HPLC method).

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Deviations:

no

GLP compliance:

no

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 6995-74-38
- Analytical purity: 99.612%
- Impurities (identity and concentrations): DMORE 0.02%

OTHER SPECIFICS:
- Name of test material (as cited in study report): DMDEE, bis(2-morpholinoethyl)-ether
- Substance type: Yellow-brown liquid
- Physical state: Liquid

Analytical method:

high-performance liquid chromatography

Type:

log Pow

Partition coefficient:

0.5

Temp.:

25 °C

pH:

9

Details on results:

Regression equation of calibration curve in measurement conditon:
log Pow = 0.957 + 1.696 x log K
r =0.999
Partition coefficient: log Pow = 0.5 (average of 2 measured values)

Conclusions:

The log Pow of the test substance was determined to be 0.5 at 25°C and pH 9.

Description of key information

The log Pow of the test substance was determined in a non GLP study according to OECD Guideline 117 to be 0.5 at 25 °C, following the HPLC method (Furutani, 1996).

Key value for chemical safety assessment

Log Kow (Log Pow):

0.5

at the temperature of:

25 °C

Additional information

The test was performed at pH 9. Under these test conditions, it is anticipated that the substance is predominantly in its non-ionized form.