Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 229-713-7
CAS number: 6674-22-2
See "Attached background material".
1,8-Diazabicyclo[5.4.0]undec-7-ene was administered by gavage to groups
of 10 male and 10 female Wistar rats at dose levels of 0 (test group 0),
15 (test group 1), 40 (test group 2) and 120 mg/kg bw/d (test group 3)
over a period of 3 months.
With regard to clinical examinations, signs of general systemic toxicity
were not observed up to the highest dose tested 120 mg/kg bw/d.
Concerning clinical pathology no treatment-related, adverse effects were
observed up to a dose of the test substance of 120 mg/kg bw/d.
Regarding pathology, all findings occurred either individually or were
biologically equally distributed over control and treatment groups. They
were considered to be incidental or spontaneous in origin and without
any relation to treatment.
All other findings occurred either individually or were biologically
equally distributed over control and treatment groups. They were
considered to be incidental or spontaneous in origin and without any
relation to treatment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again