Registration Dossier

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 26, 2011 - March 29, 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Scientifically acceptable study with detailed documentation according to a standard guideline method.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The test item and water were mixed in three different ratios (1:9, 1:1, 9:1) and pH values were measured during a water solubility test.
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: Liquid
Details on test material:
- Name of test material (as cited in study report): 1,8-Diazabicyclo-5,4,0-undecene-7
- Physical state: Liquid
- Analytical purity: 99.7%
- Lot/batch No.: O 2905
- Storage condition of test material: Ambient temperature

Results and discussion

pH valueopen allclose all
pH value:
12.6
Temp.:
23 °C
Concentration:
10.1 other: g/100g
pH value:
13.9
Temp.:
23 °C
Concentration:
50.1 other: g/100g
pH value:
15.8
Temp.:
23 °C
Concentration:
89.8 other: g/100g

Any other information on results incl. tables

 Weight of the test item [g] Amount of water added [g]  Sample size [g/100]  Ratio  Observation  pH 
 1.01 9.01  10.1  1:9  Clear, colourless and homogeneous mixture  12.6 
 5.04 5.02 50.1  1:1  Clear, colourless and homogeneous mixture  13.9 
 4.49 0.51  89.8  9:1  Clear, colourless and homogeneous slightly viscous mixture  15.8

Applicant's summary and conclusion

Conclusions:
At 23°C the pH of a 10.1 g/100g solution in water was found to be 12.6, the pH of a 50.1 g/100g solution in water was found to be 13.9, the pH of a 89.1 g/100g solution in water was found to be 15.8.
Executive summary:

The test item and water were mixed in three different ratios (1:9, 1:1, 9:1) and pH values were measured during a water solubility test. At 23°C the pH of a 10.1 g/100g solution in water was found to be 12.6, the pH of a 50.1 g/100g solution in water was found to be 13.9, the pH of a 89.1 g/100g solution in water was found to be 15.8.