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EC number: 229-713-7
CAS number: 6674-22-2
evaluation of the inherent properties of
1,8-Diazabicyclo-5-4-0-undecene-7 (CAS# 6674-22-2) is performed against
Annex XIII criteria. If insufficient data were available, the screening
criteria as laid down in ECHA Guidance on information requirements and
chemical safety assessment R.11: PBT Assessment were applied.
available evidence on degradation is not sufficient for an assessment
based on the Annex XIII criteria for persistence (P and vP). As the
substance is concluded to be neither readily nor inherently
biodegradable, it should be considered potentially P/vP from a
precautionary point of view until further data become available.
experimental OECD 305 guideline study the BCF was determined to be 3.6
at a test concentration level of 0.05 mg/L.
addition, this substance has a low log Kow (measured log Kow at pH 7.0
and 25 °C: <-2.2; BASF SE, 2011), indicating a low potential for
"T", chronic data are available for algae and daphnids, with daphnids
being the most sensitive organism in acute toxicity studies. The 21-d
NOEC was determined to be >=12 mg/L and hence is above the critical
value of 0.01 mg/L for chronic aquatic studies. The substance holds no
relevant classification. Therefore the substance is assessed to be not
toxic (not T).
It can be
concluded that the substance is neither a PBT nor a
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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