Registration Dossier
Registration Dossier
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EC number: 619-682-1 | CAS number: 224049-04-1
Endpoint summary
Administrative data
Description of key information
Additional information
The environmental profile of Isotianil is evaluated on the basis of short-term tests with species of three different trophic levels (algae, invertebrate, fish). Aquatic organisms did not show any effects up to the limit of the water solubility of the substance (< 1 mg/L) in short-term tests with fish, aquatic invertebrates and algae (LC50/EC50 > 1 mg/L, nominal).
Same observations are be reported for microorganisms, as no effects on respiration rate were observed after 3 h (EC50 > 1000 mg/L, nominal) in a respiration inhibition test with activated sludge. As no toxicological effects on microorganisms are expected up to the water solubility for Isotianil, a disturbance in the biodegradation process of a sewage treatment plant is not anticipated.
According to Annex IX, column 2(9.1) of Regulation (EC) No. 1907/2006, long-term aquatic toxicity testing shall be proposed only, if the chemical safety assessment (according to Annex I of Regulation (EC) No. 1907/2006) triggers further action in case the substance or the preparation meets the criteria for classification as dangerous according to Directive 67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT or vPvB. The hazard assessment of this substance reveals neither a need to classify the substance as dangerous for the environment, nor is it a PBT or vPvB substance. Therefore additional long-term toxicity tests on aquatic organisms are not propsed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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