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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

No effects up to the limit of water solubility.

Key value for chemical safety assessment

Additional information

One GLP-study investigating the short-term toxicity of Isotianil to Daphnia magna according to guideline JMAFF No. 12 -Nousan-8147, 2-7-2-1, comparable to OECD 202, in a static system is available (Kagoshima, 2005). No immobilization and other toxic sublethal effects on daphnids could be observed in this limit test at the tested concentration of 1 mg/L (nominal). Analytical measurement showed Isotianil was stable during the exposure period since the measured concentrations at test initiation and termination were determined to be 100% of the nominal concentration. An EC50 (48 h) > 1 mg/L (nominal) and a NOEC (48 h) ≥ 1 mg/L (nominal) were reported. It can be concluded that no toxicological effects on freshwater invertebrates are expected up to the water solubility of the substance (< 1 mg/L). Isotianil is regarded as not harmful to freshwater invertebrates.