Registration Dossier
Registration Dossier
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EC number: 619-682-1 | CAS number: 224049-04-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the limit of water solubility.
Key value for chemical safety assessment
Additional information
One GLP-study investigating the short-term toxicity of Isotianil to Daphnia magna according to guideline JMAFF No. 12 -Nousan-8147, 2-7-2-1, comparable to OECD 202, in a static system is available (Kagoshima, 2005). No immobilization and other toxic sublethal effects on daphnids could be observed in this limit test at the tested concentration of 1 mg/L (nominal). Analytical measurement showed Isotianil was stable during the exposure period since the measured concentrations at test initiation and termination were determined to be 100% of the nominal concentration. An EC50 (48 h) > 1 mg/L (nominal) and a NOEC (48 h) ≥ 1 mg/L (nominal) were reported. It can be concluded that no toxicological effects on freshwater invertebrates are expected up to the water solubility of the substance (< 1 mg/L). Isotianil is regarded as not harmful to freshwater invertebrates.
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