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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Details not reported

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
No information
Author:
Chruscielska K et al.
Year:
1971
Bibliographic source:
Przem. Chem. 50, 285-287
Reference Type:
review article or handbook
Title:
No information
Author:
Marhold J, Cizek J
Year:
1972
Bibliographic source:
Pracovni lekarstvi 9, 390-393

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
Thiophosphoryl trichloride
EC Number:
223-622-6
EC Name:
Thiophosphoryl trichloride
Cas Number:
3982-91-0
Molecular formula:
Cl3PS
IUPAC Name:
phosphorothioyl trichloride
Test material form:
not specified
Details on test material:
no data

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
no data

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
air
Details on inhalation exposure:
no data
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
4 h
Concentrations:
no data
No. of animals per sex per dose:
no data
Control animals:
no
Details on study design:
no data
Statistics:
no data

Results and discussion

Effect levels
Dose descriptor:
LC50
Effect level:
0.14 mg/L air
Exp. duration:
4 h
Mortality:
no data
Clinical signs:
other: no data
Body weight:
no data
Gross pathology:
no data

Any other information on results incl. tables

no data

Applicant's summary and conclusion

Executive summary:

LC50 = 0.14 mg/l air