Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

Currently viewing:

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Details not reported

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
No information
Author:
Chruscielska K et al.
Year:
1971
Bibliographic source:
Przem. Chem. 50, 285-287
Reference Type:
review article or handbook
Title:
No information
Author:
Marhold J, Cizek J
Year:
1972
Bibliographic source:
Pracovni lekarstvi 9, 390-393

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
Thiophosphoryl trichloride
EC Number:
223-622-6
EC Name:
Thiophosphoryl trichloride
Cas Number:
3982-91-0
Molecular formula:
Cl3PS
IUPAC Name:
phosphorothioyl trichloride
Test material form:
not specified
Details on test material:
no data

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
no data

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
air
Details on inhalation exposure:
no data
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
4 h
Concentrations:
no data
No. of animals per sex per dose:
no data
Control animals:
no
Details on study design:
no data
Statistics:
no data

Results and discussion

Effect levels
Dose descriptor:
LC50
Effect level:
0.14 mg/L air
Exp. duration:
4 h
Mortality:
no data
Clinical signs:
other: no data
Body weight:
no data
Gross pathology:
no data

Any other information on results incl. tables

no data

Applicant's summary and conclusion

Executive summary:

LC50 = 0.14 mg/l air