Registration Dossier

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
other: observation in chemical industry
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reported in brief

Data source

Reference
Reference Type:
publication
Title:
Research in industrial health in the chemical industry
Author:
Goldblatt MW
Year:
1955
Bibliographic source:
Brit J Industr Med 12, 1-20

Materials and methods

Type of study / information:
Observation of complaints of industrial workers in relation to exposure concentration and exposure time (no further details available).
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Observation of complaints of industrial workers in relation to exposure concentration and exposure time (no further details available).
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Details on study design:
Observation of complaints of industrial workers in relation to exposure concentration and exposure time (no further details available).
Exposure assessment:
measured

Results and discussion

Results:
10 ppm (70 mg/m³) , 1 hour:
--concentration causing severe toxic effects in persons
4 ppm (28 mg/m³, for more than a short time
--concentraion which is not tolerated because it leads to symptom of illness
>1 ppm (7 mg/m³),
--concentration in general atmosphere of a plant causing unsatisfactory condition in persons

Applicant's summary and conclusion