Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation / corrosion
Remarks:
no data
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary citation from review

Data source

Reference
Reference Type:
review article or handbook
Title:
Dangerous Properties of Industrial Materials.
Author:
Sax NI, Lewis RJ
Year:
1984
Bibliographic source:
7th ed., Van Nostrand Reinhold Company, New York,p. 3261

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Thiophosphoryl trichloride
EC Number:
223-622-6
EC Name:
Thiophosphoryl trichloride
Cas Number:
3982-91-0
Molecular formula:
Cl3PS
IUPAC Name:
phosphorothioyl trichloride
Details on test material:
Colorless mobile liquid, purgent odor, Bp 125 °C

Test animals

Species:
other: no data
Strain:
not specified
Details on test animals or test system and environmental conditions:
no data

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
no data
Duration of treatment / exposure:
no data
Observation period:
no data
Number of animals:
no data
Details on study design:
no data

Results and discussion

In vivo

Irritant / corrosive response data:
Thiophosphorylchloride is a corrosive irritant to skin eyes and mucous membranes

Any other information on results incl. tables

Corrosive (no further data), high irritation to skin, eyes and mucous membranes

Applicant's summary and conclusion

Interpretation of results:
corrosive
Remarks:
Migrated information