Registration Dossier
Registration Dossier
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EC number: 213-180-2 | CAS number: 928-70-1
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 3.67 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.037 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.367 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- no emission to STP expected
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 4.8 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.48 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 1.6 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The hazard assessment of this substance in the water compartment was based on the lowest short-term toxicity test results of three taxonomic groups (algae, crustaceans and fish) and the use of assessment factors. As there were neither short-term nor long-term aquatic toxicity test results available for marine organisms, the PNEC for marine water was also derived based on the aquatic fresh water toxicity. The lowest short-term aquatic toxicity of the substance was determined to daphnids (Daphnia magna) with EC50 (48h) value of 3.67 mg/L (inhibition of mobility). Hazard assessment to sewage treatment microbes was not conducted, as there are no emissions to the STP.
As there was no ecotoxicological data of the substance available for sediment-dwelling organisms or soil organisms, the PNECs for sediments and soil compartment were determined based on the partitioning method by using the PNECs derived for the water compartment and the measured adsorption coefficient of the substance (Koc 24.21). As concluded in the chemical safety assessment, PIAX and its main reaction products are degradable and will not bioaccumulate. No PNEC oral needs therefore be derived.
Conclusion on classification
The following data was used in classification and labelling of potassium isoamyl xanthate:
Aquatic acute toxicity:
48-h EC50 (immobilisation) D.magna, 3.67 mg/l (OECD 202, GLP)
72-h EC50 (growth rate) Desmodesmus subspicatus, 10.51 mg/l (OECD 201, GLP)
96-h LC50 (mortality) Danio rerio, 10 mg/l (OECD 203, GLP), read-across data from potassium isobutyl xanthate
Conclusion: no acute toxicity as the lowest toxicity value is > 1 mg/l.
Aquatic chronic toxicity:
72 -h NOEC (growth rate) Desmodesmus subspicatus,1 mg/l (OECD 201, GLP)
28-d NOEC (reproduction) Oncorhynchus mykiss, 0.79 mg/l (non guideline study (Klimisch score 3); read-across from potassium amyl xanthate)
Biodegradation:
Laboratory studies on biodegradation water screening (read-across data), no studies on the target substance:
98 % of the analogue substance was degraded in 12 days. 75 % of the substance was degraded in 5 days (modified Zahn-Wellens test (OECD 302 B). Read-across data from potassium isobutyl xanthate (PIBX). Results indicate that the test substance is inherently biodegradable.
Abiotic degradation is the driving force for the degradation of the substance in use applications. Hydrolysis is not rapid (47 to 247 days at 17 to 0 deg. C). Conclusion: Not readily biodegradable.
Bioaccumulation and/or persistence:
No potential for bioaccumulation as log Kow -0.76 (estimate with EPISUITE; US EPA 2013)
Conclusion: Aquatic chronic toxicity as the reliable short-term toxicity value (D.magna) is between 1 -10 mg/l and the substance is not considered readily biodegradable.
Classification and labeling according to CLP 1272/2008:
Aquatic Chronic Cat 2 (H411)
Classification and labeling according to DSD 67/548/EEC:
N, R51 -R53
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