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EC number: 212-039-2
CAS number: 753-73-1
From the first 10 induction exposures, the scores were as follows:
Diameter: Average = 0.6, Maximum = 1
Colour: Average = 0.75, Maximum = 2 (in one animal only at one time
point; all other scores were 1or less)
Height: Average = 0.72, Maximum = 1
From the challenge exposure after 2 weeks incubation, no score greater
than 1 was seen in any animal for either diameter, colour or height.
The sensitisation potential of dimethyltin dichloride was examined in a
Maurer optimisation test using albino guinea pigs. The experimental
procedure was that prescribed by The Food and Drug Administration of the
U.S.A. in "Appraisal of the Safety of Chemicals in Food, Drugs and
Cosmetics, "1959, p51.
The intradermal route was used for both the inital and challenge
exposures. The test substance was dissolved in a 1 part PEG to 7.3 parts
water at 0.1 % concentration.
No evidence of sensitisation was observed in a screening test performed
using the test substance on guinea pigs in a Maurer optimisation test.
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