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EC number: 212-039-2
CAS number: 753-73-1
The acute inhalation toxicity of dimethyltin dichloride was examined in
a 4 hour study using male and female Tif: RAIf (SPF) rats, in a
procedure similar to OECD 403.
Clinical observations included dyspnoea, ventral position, tremor and
ruffled fur. These symptoms became more accentuated as the concentration
Hemorrhages in the lungs were observed in animals which died during the
study, but not in those who survived.
The gravimetrically determined average concentrations used were 44 ± 6,
90 ± 7, 121 ± 3 and 167 ± 23 mg/m³.
The LC50 of a 4 hour aerosol exposure for rats of both sexes is 115
(105-126) mg/cm3 air, when evaluated
for a 14 day post-treatment observation period.
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