Registration Dossier

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Henry's Law Constant: Calculated HLC at environmental temperature (12°C): 7.6 E+04 Pa m3mol-1 

Key value for chemical safety assessment

Henry's law constant (H) (in Pa m³/mol):
76 000
at the temperature of:
12 °C

Additional information

The transfer of a substance from the water phase to the gas phase can be estimated by means of the Henry’s Law Constant (HLC). No measured value for this parameter is available. The HLC can be estimated from the ratio of the vapour pressure (VP) to the water solubility (WS).

HLC = (VP x MW)/WS

Where MW is molecular weight.

The calculated HLC value for Vi4 -D4 at environmental temperature (12°C) is very high, 7.6 E+04 Pa m3mol-1 (taken from EUSES 2.1.2). For the impurity Vi5-D5 (Impurity 1) the calculated HLC value is 1.3 E+07 Pa m3mol-1; for the impurity Vi3-D3 (Impurity 2) the calculated HLC value is 6.0 E+04 Pa m3 mol-1.