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EC number: 219-863-1 | CAS number: 2554-06-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The result is sourced from secondary literature (publication). No further information is available.
- Principles of method if other than guideline:
- Information on method and guideline not stated.
- GLP compliance:
- not specified
- Boiling pt.:
- 224 - 224.5 °C
- Atm. press.:
- 758 mm Hg
- Boiling pt.:
- 111 - 112 °C
- Atm. press.:
- 10 mm Hg
- Conclusions:
- A boiling point of 224-224.5°C at 758 mmHg was reported in a secondary source. The original reference was not available for review and no further information is available. The reliability of this result is not assignable.
- Endpoint:
- boiling point
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- Please refer to attached justification documents
- Principles of method if other than guideline:
- The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
The model is an adaptation of the existing SRC model MPBPVPWIN v 1.43, which is a component of the EPI Suite. This existing model is based on fragment values. That is, the chemical structure is broken down into its constituent functional groups, and the contribution of each group toward the overall boiling point is calculated. Certain correction factors may also apply. Whilst this method is good in principle, the model was developed using a wide range of organic chemicals and only a few organosilicon compounds. Therefore, a validation procedure was undertaken to assess the applicability of the model to other organosilicon compounds excluding chlorosilanes and alkoxysilanes. It was noted that the MBBPVPWIN model gave a systematic error; therefore, the current model was developed to correct this. The current model is a linear regression based QSAR, with the boiling point prediction from MPBPVPWIN as the descriptor. The adapted model applies to other organosilanes except chlorosilanes and alkoxysilanes. - Boiling pt.:
- 220 °C
- Atm. press.:
- 1 013 hPa
- Boiling pt.:
- 496 K
- Atm. press.:
- 1 013 hPa
- Conclusions:
- A boiling point value of 220°C was obtained using an accepted calculation method. The result is considered to be reliable.
- Endpoint:
- boiling point
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- Please refer to attached justification documents
- Principles of method if other than guideline:
- The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
- Boiling pt.:
- ca. 170 °C
- Atm. press.:
- 1 013 hPa
- Boiling pt.:
- 444 K
- Atm. press.:
- 1 013 hPa
- Conclusions:
- A boiling point value of approximately 170°C was obtained for impurity 2 using an accepted calculation method. The result is considered to be reliable.
- Endpoint:
- boiling point
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- Please refer to attached justification documents
- Principles of method if other than guideline:
- The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
- Boiling pt.:
- ca. 270 °C
- Atm. press.:
- 1 013 hPa
- Boiling pt.:
- 540 K
- Atm. press.:
- 1 013 hPa
- Conclusions:
- A boiling point value of approximately 270°C was obtained for impurity 1 using an accepted calculation method. The result is considered to be reliable.
Referenceopen allclose all
Description of key information
Boiling point (2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane): 220°C (QSAR)
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 220 °C
Additional information
A predicted boiling point of 220°C was determined for the registered substance, Vi4-D4, using a validated QSAR estimation method. The predicted value is supported by a measured boiling point value of 216.6 - 226.5°C at 1009 ± 1 hPa determined for the low purity form of the registration substance using a Differential Scanning Calorimetry (DSC) method in accordance with OECD Test Guideline 103 and in compliance with GLP. The predicted and measured values are in good agreement; the predicted value is selected as the key value for Chemical Safety Assessment.
This conclusion is supported by boiling point of 224 -224.5°C at 758 mmHg and 111 -112°C at 10 mmHg which was reported for Vi4-D4 in a secondary source to which no reliability could be assigned.
2,4,6,8,10 -Pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane Vi5-D5 (CAS No: 17704-22-2; impurity 1) and 2,4,6-trimethyl-2,4,6-trivinylcyclotrisiloxane Vi3-D3 (CAS No: 3901-77-7; impurity 2) may be present as impurities. The boiling points of the impurities have been predicted using a validated QSAR estimation method. Boiling points of approximately 270°C and 170°C were predicted for Vi5-D5 and Vi3-D3 respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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