Registration Dossier

Environmental fate & pathways

Hydrolysis

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Justification for type of information:
Experimental study made available by ECHA
Qualifier:
according to
Guideline:
other: 92/69/EEC C7
Principles of method if other than guideline:
Rate of hydrolysis of test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) was determined.
GLP compliance:
yes
Specific details on test material used for the study:
- Name of test material (IUPAC name): (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS)
- Common name: Lokanol
- Molecular formula: C15H26O
- Molecular weight: 222.3694 g/mol
- InChl: 1S/C15H26O/c1-13(2)10(6-12-8-15(12,13)4)5-11-7-14(11,3)9-16/h10-12,16H,5-9H2,1-4H3
- Substance type: Organic
pH:
4
Temp.:
25 °C
Hydrolysis rate constant:
0 s-1
DT50:
341.833 d
Remarks on result:
other: 8204 hours
pH:
7
Temp.:
25 °C
Hydrolysis rate constant:
0 s-1
DT50:
> 365 d
Remarks on result:
other: >8760 hours
pH:
9
Temp.:
25 °C
Hydrolysis rate constant:
0 s-1
DT50:
> 365 d
Remarks on result:
other: >8760 hours
Conclusions:
The half life of test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) at pH 4,7 and 9 is 8204,> 8760 and > 8760 hours repectively.
Executive summary:

Based on available data from secondary source, The half life of test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) at pH 4,7 and 9 is 8204,> 8760 and > 8760 hours repectively.Therefore it is concluded that the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) is stable.

Description of key information

The half life of test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) at pH 4,7 and 9 is 8204,> 8760 and > 8760 hours repectively.

Key value for chemical safety assessment

Half-life for hydrolysis:
8 760 h
at the temperature of:
25 °C

Additional information

Based on available data from secondary source, The half life of test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) at pH 4,7 and 9 is 8204,> 8760 and > 8760 hours repectively.Therefore it is concluded that the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) is stable.