Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Justification for type of information:
Experimental study made available by ECHA
Qualifier:
according to
Guideline:
other: 92/69/EEC, C1 OECD 203
Principles of method if other than guideline:
Short term toxicity study of test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) on fish Cyprinus carpio was carried out for 96 hrs.
GLP compliance:
yes
Specific details on test material used for the study:
- Name of test material (IUPAC name): (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS)
- Common name: Lokanol
- Molecular formula: C15H26O
- Molecular weight: 222.3694 g/mol
- InChl: 1S/C15H26O/c1-13(2)10(6-12-8-15(12,13)4)5-11-7-14(11,3)9-16/h10-12,16H,5-9H2,1-4H3
- Substance type: Organic
Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: Acetone (used as a pre-solvent)
0.01%
Test organisms (species):
Cyprinus carpio
Test type:
semi-static
Water media type:
freshwater
Hardness:
240 mg CaCO3/L
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
1 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
1 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
1 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
1 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
2.3 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
0.2 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Details on results:
%Concentration loss over test: 70 ... 84
Validity criteria fulfilled:
not specified
Conclusions:
The LC50 value obtained was 1 mg/l when the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) exposed to Cyprinus carpio for 96 hrs.
Executive summary:

Determination of short term toxicity of the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) (198404-98-7) was studied on Cyprinus carpio for 96 hours and study was performed according to the other guideline 92/69/EEC, C1 OECD 203 by performing semi static system.The test was performed at diffierent durations i.e. 24,72 and 96 hours. The LC50 and NOEC values for 96 hours is considered to be 1 mg/l and 0.2 mg/l.

Based on the LC50 value of the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS), it was concluded that the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) was considered as toxic and can be consider to be classified as aquatic chronic /acute 1 category as per CLP classification criteria.

Description of key information

Determination of short term toxicity of the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) (198404-98-7) was studied on Cyprinus carpio for 96 hours and study was performed according to the other guideline 92/69/EEC, C1 OECD 203 by performing semi static system.The test was performed at diffierent durations i.e. 24,72 and 96 hours. The LC50 and NOEC values for 96 hours is considered to be 1 mg/l and 0.2 mg/l.

Based on the LC50 value of the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS), it was concluded that the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) was considered as toxic and can be consider to be classified as aquatic chronic /acute 1 category as per CLP classification criteria.

Key value for chemical safety assessment

LC50 for freshwater fish:
1 mg/L

Additional information

Determination of short term toxicity of the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) (198404-98-7) was studied on Cyprinus carpio for 96 hours and study was performed according to the other guideline 92/69/EEC, C1 OECD 203 by performing semi static system.The test was performed at diffierent durations i.e. 24,72 and 96 hours. The LC50 and NOEC values for 96 hours is considered to be 1 mg/l and 0.2 mg/l.

Based on the LC50 value of the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS), it was concluded that the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) was considered as toxic and can be consider to be classified as aquatic chronic /acute 1 category as per CLP classification criteria.