Registration Dossier
Registration Dossier
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EC number: 201-898-9 | CAS number: 89-32-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March - May 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- test item is unstable in water, therefore the hydrolysis product PMA was tested; refer to analogue justification provided in IUCLID section 13
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- - Description: white powder
- Batch number: 8M30N
- Storage conditions: room temperature in the dark upto 04 April 2008, thereafter at approximately 4°C, over silica gel, in the dark - Water solubility:
- 8.83 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- Remarks on result:
- other: results of preliminary test
- Key result
- Water solubility:
- 8.56 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 8.56
- Remarks on result:
- other: results of main test
- Conclusions:
- The water solubility of the test material has been determined to be 8.56 g/ at 20.0 ± 0.5°C and a pH-value of 8.56.
- Executive summary:
The study was conducted according to EC method A.6, using the shake-flask method. In conclusion, the water solubility of the test item was determined to be 8.56 g/L at 20°C. The pH value was found to be 8.56
Reference
Description of key information
As the substance to be registered, PMDA, is unstable in water, the corresponding hydrolysis product Pyromellitic acid (PMA) was tested. The study was conducted according to EC method A.6, using the shake-flask method. In conclusion, the water solubility of PMA was determined to be 8.56 g/L at 20°C. The pH value was found to be 8.56. In addition, the estimated water solubility of PMDA is reported in literature to be approx. 130 mg/l at 25°C.
Key value for chemical safety assessment
- Water solubility:
- 8.56 g/L
- at the temperature of:
- 20 °C
Additional information
Source: GLP-report
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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