Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The registered substance is a highly reactive dianhydride hydrolyzing in water within approx. 20 minutes. Testing of the substance as such was not possible, therefore the corresponding Pyromellitic acid PMA was tested (read-across):

Short-term toxicity to fish

The study was performed to assess the acute toxicity of the test material to rainbow trout (Oncorhynchus mykiss). The method followed that described in the OECD Guidelines No. 203, "Fish, Acute Toxicity Test". The 96 -Hour LC50 based on mean measured test concentrations was greater than 100 mg/l and correspondingly the No Observed Effect Concentration was 100 mg/l.

Short-term toxicity to aquatic invertebrates

The study was performed to assess the acute toxicity of the test material to Daphnia magna. The method followed that described in the OECD Guidelines No 202, "Daphnia sp, Acute Immobilisation Test". The 48-Hour EC50 for the test material to Daphnia magna based on mean measured test concentrations was 63 mg/l with 95% confidence limits of 56 -71 mg/l. The No Observed Effect Concentration was 32 mg/l.

Acute toxicity to green algae

The study was performed to assess the effect of the test material on the growth of the green alga Desmodesmus subspicatus. The method followed that described in the OECD Guidelines No 201, "Freshwater Alga and Cyanobacteria, Growth Inhibition Test".

In terms of growth rate, exposure of Desmodesmus subspicatus to the test material gave an ErC50 (0 - 72 h) value of 8.1 mg/l. The Lowest Observed Effect Concentration based on inhibition of growth rate was 12.5 mg/l and the No Observed Effect Concentration was 6.25 mg/l.

In terms of yield, exposure of Desmodesmus subspicatus to the test material gave an EyC50(0 - 72 h) value of 7.9 mg/l. The Lowest Observed Effect Concentration based on yield was12.5 mg/l and the No Observed Effect Concentration was 6.25 mg/l.

In terms of biomass integral (area under growth curve), exposure of Desmodesmus subspicatus to the test material gave an EbC50 (0 - 72 h) value of 8.8 mg/l The Lowest Observed Effect Concentration based on inhibition of biomass integral was 12.5 mg/l and the No Observed Effect Concentration was 6.25 mg/l.

Additional information

Source: GLP-reports and expert assessments