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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Experimental test result performed using standard methods
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
The water solubility determination of test item 2,2,2-trichloroethane-1,1-diol(CAS No; 302-17-0) was done as per the HPLC method.
GLP compliance:
no
Type of method:
flask method
Specific details on test material used for the study:
- Name of test material: 2,2,2-Trichloroethane-1,1-diol (Chloral hydrate)
- Molecular formula: C2-H3-Cl3-O2
- Molecular weight: 165.4026g/mol
- Smiles notation: C(C(O)O)(Cl)(Cl)Cl
- InChl: RNFNDJAIBTYOQL-UHFFFAOYSA-N
- Substance type: Organic
- Physical state: Solid
Key result
Water solubility:
443 695.65 mg/L
Temp.:
25 °C
Remarks on result:
other: pH details not available
Details on results:
The experimental water solubility for the test chemical by the HPLC method was found to be 443695.65 mg/l (443.695 g/l) @25oC

The water solubility determination of test item CAS No: 302-17-0 was done by HPLC. The mean water solubility was found to be 443695.65 mg/l (443.695 g/l)@250C

Conclusions:
The water solubility determination of test item CAS No: 302-17-0 was done by HPLC. The mean water solubility was found to be 443695.65 mg/l (443.695 g/l) @25°C indicating that the chemical is very soluble in water.
Executive summary:

The water solubility determination of test item 2,2,2-trichloroethane-1,1-diol (CAS No; 302-17-0) was done as per the HPLC method. The solubility of CAS No. 302-17-0 in water was found to be 443695.65 mg/L (443.695 g/l)@ 250C. This value indicates that the substance is very soluble in water.

Description of key information

The water solubility determination of test item CAS No: 302-17-0 was done by HPLC. The mean water solubility was found to be 443695.65 mg/l (443.695 g/l) @25°C indicating that the chemical is very soluble in water.

Key value for chemical safety assessment

Water solubility:
443 695.65 mg/L
at the temperature of:
25 °C

Additional information

The water solubility determination of test item 2,2,2-trichloroethane-1,1-diol (CAS No; 302-17-0) was done as per the HPLC method. The solubility of CAS No. 302-17-0 in water was found to be 443695.65 mg/L (443.695 g/l)@ 250C. This key study value and other suporting data from different source also indicates that the substance is very soluble in water.