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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Experimental test result performed using standard methods
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
The water solubility determination of test item 2,2,2-trichloroethane-1,1-diol(CAS No; 302-17-0) was done as per the HPLC method.
GLP compliance:
no
Type of method:
flask method
Specific details on test material used for the study:
- Name of test material: 2,2,2-Trichloroethane-1,1-diol (Chloral hydrate)
- Molecular formula: C2-H3-Cl3-O2
- Molecular weight: 165.4026g/mol
- Smiles notation: C(C(O)O)(Cl)(Cl)Cl
- InChl: RNFNDJAIBTYOQL-UHFFFAOYSA-N
- Substance type: Organic
- Physical state: Solid
Key result
Water solubility:
443 695.65 mg/L
Temp.:
25 °C
Remarks on result:
other: pH details not available
Details on results:
The experimental water solubility for the test chemical by the HPLC method was found to be 443695.65 mg/l (443.695 g/l) @25oC

The water solubility determination of test item CAS No: 302-17-0 was done by HPLC. The mean water solubility was found to be 443695.65 mg/l (443.695 g/l)@250C

Conclusions:
The water solubility determination of test item CAS No: 302-17-0 was done by HPLC. The mean water solubility was found to be 443695.65 mg/l (443.695 g/l) @25°C indicating that the chemical is very soluble in water.
Executive summary:

The water solubility determination of test item 2,2,2-trichloroethane-1,1-diol (CAS No; 302-17-0) was done as per the HPLC method. The solubility of CAS No. 302-17-0 in water was found to be 443695.65 mg/L (443.695 g/l)@ 250C. This value indicates that the substance is very soluble in water.

Description of key information

The water solubility determination of test item CAS No: 302-17-0 was done by HPLC. The mean water solubility was found to be 443695.65 mg/l (443.695 g/l) @25°C indicating that the chemical is very soluble in water.

Key value for chemical safety assessment

Water solubility:
443 695.65 mg/L
at the temperature of:
25 °C

Additional information

The water solubility determination of test item 2,2,2-trichloroethane-1,1-diol (CAS No; 302-17-0) was done as per the HPLC method. The solubility of CAS No. 302-17-0 in water was found to be 443695.65 mg/L (443.695 g/l)@ 250C. This key study value and other suporting data from different source also indicates that the substance is very soluble in water.