Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-961-6 | CAS number: 112-34-5
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 1.1 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 11 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.11 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 4.4 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.44 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.32 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 56 mg/kg food
- Assessment factor:
- 90
Additional information
Formula for the calculation of PNECsed using the equilibrium partitioning approach for sediment and a Koc prediction based on alcohols:
PNEC(sed) = (Ksed-water x PNEC(aqua) / RHOsed) * 1000
PNEC(sed) Predicted No Effect Concentration in sediment [mg/kg, wet weight]
Ksusp-water partition coefficient sediment / water [0.997 m3/m3]
RHOsed bulk density of sediment matter [1150 kg/m3]
PNECaqua Predicted No Effect Concentration in water [as above]
Formula for the calculation of PNECsed using the equilibrium partitioning approach for soil:
PNEC(soil) = (Ksoil-water x PNEC(aqua) / RHOsoil) * 1000
PNEC(soil) Predicted No Effect Concentration in sediment [mg/kg, wet weight]
Ksoil-water partition coefficient sediment / water [0.433 m3/m3]
RHOsoil bulk density of soil matter [1700 kg/m3]
PNECaqua Predicted No Effect Concentration in water [as above]
The PNEC oral is derived using the critical oral mammalian NOAEL (in mg/kg bw ) as a starting point. This is then converted to a NOEC (in mg/kg food) using the conversion factors in table R10-12 of the guidance from which the PNEC is derived by using the appropriate assessment factor in table R10 -13.
Conclusion on classification
The very low toxicity of 2 -(2 -butoxyethoxy)ethanol to aquatic species coupled with its ready biodegradability mean that it does not meet the criteria for classification under either directive 67/548 or regulation 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
