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Description of key information

Elimination: 97% eliminated in 24hrs, mainly in urine as 2-(2-butoxyethoxy)acetic acid.
Dermal absorption rate: Rat: 0.73-1.46mg/cm2/hr

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Additional information

A study examined the absorption and elimination of radio-labelled 2 -(2 -butoxyethoxy)ethanol in rats following 24hr dermal occluded exposure and established that the main route of elimination is overwhelmingly via the urine and the metabolite 2 -(2 -butoxyethoxy)acetic acid. The glucoronidate conjugate was also found at significant levels (5 -8%). Females appeared to absorb and therefore excrete larger quantities than males and the dermal absorption rate was estimated to be 0.73 and 1.46mg/cm2/hr for males and females respectively. Washing studies showed that 90%+ of externally applied substance could be removed after 5 minutes exposure by skin washing.

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