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Toxicological information

Neurotoxicity

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Administrative data

Description of key information

No evidence of neurotoxicity.

Key value for chemical safety assessment

Additional information

A sub-chronic dermal toxicity in rats examined neurotoxicity using a functional observational battery and locomotor analysis.  There was no indication of any neurotoxic effect  and there were no abnormal gross or neuropathological  changes.  The only finding of note was scab formation on 5 females at the site of repeated application of the neat substance in the high dose animals.

Justification for classification or non-classification

No requirement for classification under either directive 67/548 or regulation 1272/2008.