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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

Daphnia magna. 48hr EC50 >100mg/l (OECD 202)
Daphnia magna. 24hr EC50 = 1750mg/l (protocol: no data)
Daphnia magna. 24hr EC50 = 3200mg/l (protocol: no data)
Dapnia magna 48hr LC50 >1000mg/l (protocol: US EPA)
Daphnia magna. 48hr EC50 = 2209mg/l (protocol: QSAR)

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
1 101 mg/L

Additional information

A number of studies have been carried out however there is no single 48hr study that permits the determination of an actual EC50 value. The most reliable study result is a GLP protocol limit test where clearly no effects were observed at the highest tested concentration of 100mg/l. Other experimental studies are only for 24hr exposure periods. A QSAR predicts a 48hr EC50 for Daphnia magna of 2209mg/l. Clearly 2 -(2 -butoxyethoxy) ethanol is practically non-toxic to invertebrates. For the purposes of risk assessment, there is enough evidence to support a conclusion that the 48hr EC50 for daphnia is likely to be greater than 1101mg/l.