Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Basic toxicokinetics

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Administrative data

Endpoint:
basic toxicokinetics, other
Type of information:
experimental study
Adequacy of study:
weight of evidence

Data source

Reference
Reference Type:
publication
Title:
Comparison of the urinary excretion of arsenic metabolites after a single oral dose of sodium arsenite, monomethylarsonate or dimethylarsinate in man
Author:
Buchet, J.P. et al.
Year:
1981
Bibliographic source:
Int. Arch. Occup. Environ. Health 48, 71–79

Materials and methods

Test material

Constituent 1
Reference substance name:
sodium dioxoarsenate (and others)
IUPAC Name:
sodium dioxoarsenate (and others)

Results and discussion

Main ADME results
Type:
other:
Results:
Based on the reported findings, an average of 60% of total arsenic intake is assumed to be excreted via urine. For details, please refer to endpoint summary/discussion.

Applicant's summary and conclusion