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Ecotoxicological information

Toxicity to other aquatic organisms

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Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well documented and performed study according to scientific standards

Data source

Reference
Reference Type:
publication
Title:
Chronic Exposure to Pentavalent Arsenic of Larval Leopard Frogs (Rana pipiens): Bioaccumulation and Reduced Swimming Performance
Author:
Chen TH, Gross JA, Karasov WH
Year:
2009
Bibliographic source:
Ecotoxicology 18, 587-593

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
long-term toxicity of amphibia
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
Rana pipiens

Study design

Test type:
not specified
Water media type:
freshwater
Total exposure duration:
113 d

Test conditions

Nominal and measured concentrations:
nominal concentrations were anlytically confirmed: control, 10, 20, 150, 500 and 1000 microg/L

Results and discussion

Effect concentrations
Duration:
44 d
Dose descriptor:
NOEC
Effect conc.:
1.026 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
dissolved
Basis for effect:
other: mortality, growth

Applicant's summary and conclusion

Conclusions:
A reliable long-term NOEC value of 1.03 mg As/L is reported for the growth of the freshwater amphibian species Rana pipiens, and this NOEC value is considered for the Chemicals Safety Assessment.