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Ecotoxicological information

Toxicity to birds

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Administrative data

Endpoint:
toxicity to birds
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Not a guideline study, but well conducted and reported study

Data source

Reference
Reference Type:
publication
Title:
Arsenic Residues in Eggs from Laying Hens Fed with a Diet Containing Arsenic (III) Oxide
Author:
Holcman A, Stibilj V
Year:
1997
Bibliographic source:
Archives of Environmental Contamination and Toxicology 32, 407-410

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
feeding study on Gallus gallus domesticus
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Dose method:
feed

Test organisms

Test organisms (species):
other: Gallus gallus domesticus
Details on test organisms:
Rhode Island Red Hens

Study design

Total exposure duration (if not bolus):
19 d
No. of animals per sex per dose and/or stage:
A control group was included in the trial. The hens from each group were formed into three subgroups. The eggs of two hens, laid in three days, formed a composite sample.
Nominal and measured doses / concentrations:
7.5, 15.0, 30.0 mg As/kg diet

Results and discussion

Effect levels
Duration (if not bolus):
19 d
Dose descriptor:
NOEL
Effect level:
2.24 mg/kg bw/day (nominal)
Conc. / dose based on:
element
Basis for effect:
other: survival, feed consumption, number of eggs per hen, body weight, average egg weight
Remarks on result:
other: corresponds to a NOEC of 30mg As / kg diet

Applicant's summary and conclusion

Conclusions:
Reproduction, growth, behavior and survival were not significantly affected at 2.24 mg/kg bw/day (30 mg As/kg diet).