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Ecotoxicological information

Toxicity to other above-ground organisms

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Administrative data

Endpoint:
toxicity to other above-ground organisms
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Publication has been subject to peer and adminsitrative review.

Data source

Reference
Reference Type:
secondary source
Title:
Ecological Soil Screening Levels for Arsenic Interim Final
Author:
Anonymous
Year:
2005
Bibliographic source:
U.S. Environmental Protection Agency; Office of Solid Waste and Emergency Response

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
review of literature data based on elemental arsenic
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Assessment based on elemental As

Test organisms

Test organisms (species):
other: various species, including rats, mice, rabbits, guinea pigs, dogs and goats, pigs

Study design

Study type:
other: literature review and derivation of a toxicity reference value

Results and discussion

Effect concentrations
Duration:
8 wk
Dose descriptor:
other: NOAEL
Effect conc.:
1.04 other: mg/kg bw/d
Nominal / measured:
not specified
Conc. based on:
element
Basis for effect:
growth
Remarks on result:
other: Canis familiaris; based on study by Neiger and Osweiler (1989)

Applicant's summary and conclusion

Conclusions:
Based on the assessment of available literature data on As toxicity to mammals (i.e. 138 individual study results), the highest bounded NOAEL that is lower than the lowest bounded LOAEL for reproduction, growth or survival of a mammalian species is 1.04 mg As/kg bw day for the growth of a dog (Canis familiaris) based on a study by Neiger and Osweiler (1989). Applying a conversion factorr of 40 (g bw/g diet per day), this NOAEL corresponds to a NOEC of 41.6 mg As/kg diet.