Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Reliable studies (Klimisch score 1 or 2) that can be used in the assessment of the bioaccumulation potential of thiourea are not available. Nonetheless, a new bioaccumulation study in aquatic species does not need to be conducted, as in accordance with column 2 of REACH Annex IX the substance has a low potential for bioaccumulation (log octanol water partition coefficient less than 3).

This statement is further supported by two Klimisch 3 studies conducted by Geyer et al. (1984) and Freitag et al. (1985):

- Geyer et al. (1985) exposed algae (Chlorella) to 14C-labelled thiourea for at least 24 h at room temperature (20-25 °C). The bioaccumulation factor for the alga Chlorella was determined to be 54.

- Freitag et al. (1985) experimentally determined the bioconcentration of thiourea in the fish Leuciscus idus melanotus after 3 days of exposure to be < 10.

Due to the information and results presented above, it can be concluded that thiourea does not have a significant potential for bioaccumulation. Following the precautionary principle the higher BCF value of 54 is used as key value in the risk assessment.

Data on terrestrial bioaccumulation are not available.