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Ecotoxicological information

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Thiourea is non-toxic to earthworms. Two 28-d studies on the toxicity to Eisenia foetida (endpoint recorded: mortality) are available, reporting LC50 values above 1000 mg/kg substrate (Korte & Freitag, 1984) and equal to 3,550 mg/kg substrate (Friesel et al., 1984), respectively.

Several plant species were tested in the plant toxicity assessment of thiourea. The most sensitive reliable EC50 (10 d) of 52.1 mg/kg soil dw is reported by Günther & Pestemer (1990).

The toxicity of thiourea to soil microorganisms was investigated in several studies (Lashen & Starkey, 1970; Pandey et al. 1976; Zacherl & Amberger, 1990; Kubota & Asami, 1985). It could be shown that thiourea is toxic to soil microorganisms and inhibits growth as well as nitrification. Acclimatisation to thiourea occurs over time and thiourea can be decomposed.

Besides, five study abstracts were available for review that describe the chemosterilising effects of thiourea on beetles and flies (Shanker at al., 1990; Pandey & Pandey, 1991; Bhide, 1991; Chaudhry &Tripathi, 1976; Deepak & Chaudhry, 1979). The terrestrial invertebrates examined in these studies all live above-ground and are therefore outside the scope of REACH (see ECHA Guidance Document R.7c, p. 105). This information is of supplemental character only.