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EC number: 200-543-5 | CAS number: 62-56-6
In a dermal sensitization study with Thiourea (0.5-10%) male guinea pigs (pirbright white) were tested using the method of Magnusson and Kligman. Induction was performed intradermal. Penicillin G-Na was used as positive control.
In this study Thiourea is not a dermal sensitizer.
In a dermal sensitization study with 0.1 ml Thiourea (0.5–10 %) male guinea pigs were tested using the method of Magnusson and Kligman. In this study Thiourea is not a dermal sensitizer. Several case reports on human exposure are available indication a low degree of sensitization. The number of reports are not considered to represent a "substantial number" as required for a classification under CLP. In addition it is not clear whether or not they are attributable to Thiourea derivatives. In several cases thiourea derivatives and not thiourea as such were reported to cause contact dermatitis.
Thiourea is not classified based on a negative Guinea Pig Maximisation Test.
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