Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-904-5
CAS number: 111-75-1
An assessment of the toxicokinetic behaviour
of butylethanolamine was performed, taking into account the chemical
structure, the available physico-chemical-data and the available
toxicity data. BEA is expected to be absorbed from GI tract by passive
diffusion. A high systemic availability via dermal and inhalation routes
is unlikely. BEA is expected to be predominantly distributed into the
intravascular compartment due to its MW of 117.2 g/mol and high water
solubility (1000 g/L). BEA can also enter the cell inner (LogPow of
0.62). No risk for accumulation is expected for BEA (LogPow is < 3.0).
Possible reactions: hydroxylation and oxidation by Phase I enzymes with
subsequent conjugation reactions. BEA is expected to be excreted
primarily via the urine due to it MW (117.2 g/mol), vapour pressure
(13.94 Pa) and the high water solubility (1000 g/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again