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EC number: 203-904-5
CAS number: 111-75-1
for assessing PBT properties are defined in Annex XIII, REACH Regulation
(EC) No. 1907/2006. Further details are laid down in ECHA Guidance on
Information Requirements and Chemical Safety Assessment; Chapter R.11:
PBT Assessment (May 2008). The assessment of PBT / vPvB properties is
based upon a separate assessment for each parameter (i.e. P or vP, B or
B and T). Substances are only assigned as PBT or vPvB when they fulfil
the criteria for all three properties (persistency, bioaccumulation and
toxicity in case of PBT substance) or both criteria (i.e. very
persistent and very bioaccumulative) in case of vPvB, respectively.
on biodegradability test results (readily biodegradable) and reliable
supporting QSAR information, Butylaminoethanol is considered neither as
persistent (not P) nor as very persistent (not vP). The
B criterion (bioaccumulative substance) is not fulfilled, due to the
experimentally determined logPow of 0.64 (BASF AG, 1993) and the
predicted Bioconcentration factor (BCF) far below the trigger value of
100 L/kg (3.17 L/kg; Chemservice S.A., 2017). Due to the lack of a
long-term toxicity potential, also the T criterion is not fulfilled.
Furthermore, no classification exists as carcinogenic, mutagenic or
toxic for reproduction according to Regulation (EC) No. 1272/2008. The
test substance is neither classified as "T, R48" or as "Xn, R48" based
on the criteria laid down in Directive 67/548/EEC nor as STOT RE
category 1 or 2 so far.
conclusion, Butylaminoethanol fulfils
none of the relevant PBT/vPvB criteria and therefore, making all
allowances for regulatory parameters available, the substance is neither
PBT nor vPvB.
Neither direct nor indirect exposure of the
solely substance Butylaminoethanol to the environmental compartment is
intended. Workers may be exposed via the dermal route due to substance
handling during manufacture.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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