Registration Dossier

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 26th, 2016.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0 Pa

The vapour pressure of the test item at 20ºC and 25ºC was calculated on the basis of equation log (p) = f (1/t) = a-b/(t+273.15) where: p – vapour pressure in Pa, t – temperature in ºC, obtained for four measurement points: 148.1ºC, 154.2ºC, 158.1ºC and 162.7ºC. The determined vapour pressure is:

Test sample

Vapour pressure at 20ºC

[Pa]

Vapour pressure at 25ºC

[Pa]

Naringin 2.25·10-11 7.24·10-11




Conclusions:
The vapour pressure of the test item is 2.25E-11 Pa at 20ºC and 7.24E-11 Pa at 25ºC.
Executive summary:

The study of the vapour pressure using effusion method was performed in accordance with the method EU A4 - Knudsen cell (GLP study). The vapour pressure of the test item was found to be 2.25E-11 Pa at 20ºC and 7.24E-11 Pa at 25ºC.

Description of key information

Key study. Method according to EU A.4, GLP study. The vapour pressure of the test item is 2.25E-11 Pa at 20ºC and 7.24E-11 Pa at 25ºC.

Key value for chemical safety assessment

Vapour pressure:
2.25 Pa
at the temperature of:
20 °C

Additional information

The study of the vapour pressure using effusion method was performed in accordance with the method EU A4 - Knudsen cell (GLP study).The vapour pressure of the test item was found to be 2.25E-11 Pa at 20ºC and 7.24E-11 Pa at 25ºC.