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Physical & Chemical properties

Melting point / freezing point

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Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Reference:
Composition 1
Principles of method if other than guideline:
Data from peer reviewed handbook. No information provided on methods.
GLP compliance:
not specified
Test material information:
Composition 1
Key result
Melting / freezing pt.:
171 °C
Decomposition:
no
Sublimation:
no
Conclusions:
According to peer reviewed handbook data, the melting point for naringin is 171ºC.
Executive summary:

Hawley's Condensed Chemical Dictionary, 13th Ed (Handbook, peer reviewed) states that the melting point for naringin is 171ºC.

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Reference:
Composition 1
Principles of method if other than guideline:
Data from peer reviewed handbook. No information provided on methods.
GLP compliance:
not specified
Test material information:
Composition 1
Key result
Melting / freezing pt.:
171 °C
Sublimation:
no
Remarks on result:
other: containing 2 mol water.
Key result
Melting / freezing pt.:
83 °C
Sublimation:
no
Remarks on result:
other: containing 6-8 mol water.
Conclusions:
According to peer reviewed handbook data, the melting point for naringin dihydrate is 171ºC.
Executive summary:

The Merck Index, 14th Ed (Handbook, peer reviewed) states that the melting point for naringin dihydrate is 171ºC, and the melting point for naringin when crystallized from water, containing 6 to 8 mols H2O is 83ºC.

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Reference:
Composition 1
Principles of method if other than guideline:
Experimental database match from EPI Suite v4.11. No details provided on method.
GLP compliance:
no
Type of method:
other: not specified.
Test material information:
Composition 1
Specific details on test material used for the study:
- CAS No. 10236-47-2
- SMILES: O4C(C)C(O)C(O)C(O)C4OC5C(O)C(O)C(CO)OC5Oc1cc(O)c2C(=O)CC(c3ccc(O)cc3)Oc2c1
Key result
Melting / freezing pt.:
83 °C
Remarks on result:
other: Experimental database match. No further details provided.

EPI Suite v4.11 reports the melting point of the test item to be 83ºC (experimental database match).

Conclusions:
The melting point of the test item is 83ºC.
Executive summary:

According to EPI Suite v4.11 (experimental database match), the melting point of the test item is 83ºC.

Description of key information

Weight of evidence. Based on peer reviewed handbook data, the test item, with 6-8 mols H2O, has a melting point of 83ºC, whereas with 2 mols H2O, it has a melting point of 171ºC.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
83 °C

Additional information

Weight of Evidence: The Merck Index, 14th Ed (Handbook, peer reviewed) states that the melting point for naringin dihydrate is 171ºC. Hawley's Condensed Chemical Dictionary, 13th Ed (Handbook, peer reviewed) states that the melting point for naringin is 171ºC. On the other hand, The Merck Index, 14th Ed (Handbook, peer reviewed) states that the melting point for naringin, when crystallised from water (6 -8 mols H2O), is 83ºC, and according to EPI Suite v4.11 (experimental database match), the melting point of the test item is 83ºC. Based on the available data, the test item has a melting point of 83ºC.