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EC number: -
CAS number: -
data is being read across from the source study that tested
Hydrocarbons, C12-C16, isoalkanes, cyclics, <2% aromatics based on
analogue read across.
To assess acute inhalation toxicity, MRD-95
-289 was administered via individual whole-body inhalation chambers for
four hours to ten Crl:CDBR rats at a total chamber concentration of 5991
mg/m3 (5428 mg/m3 aerosol, 562 mg/m3
vapor). Animals were observed for fourteen days following exposure.
There were no mortality or gross pathological alterations in the
animals, with the exception of two animals that displayed scabs and one
with a necrotic and truncated tail. Based on the conditions of the
study, the LC50 for acute inhalation exposure to an aerosol atmosphere
of MRD-95 -289 is greater than 5991 mg/m3.
This finding does not warrant classification
of MRD-95 -289 as an acute inhalation toxicant under the new Regulation
(EC) 1272/2008 on classification, labeling, and packaging of substances
and mixtures (CLP) or under the Directive 67/518/EEC for dangerous
substances and Directive 1999/45/EC for preparations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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