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EC number: 937-158-3
CAS number: -
Table 1 : Summary of Dermal Scores / Test Material: Gem Sea125 Lot 20060466
data is being read across from the source study that tested
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, < 2% aromatics
based on analogue read across.
The study was conducted in order to
determine the dermal irritation and the sensitisation potential of Gem
Seal 25 in 53 volunteers. The test substance was diluted at 10% in
petrolatum. Semi-occlusive patches were applied to skin of volunteers
for a period of 24 hours. Prior to the application, the test area was
wiped with 70% isopropyl alcohol and allowed to dry. After 9
applications during the induction period the sites were graded for
dermal irritation. Following a 2-week rest period, the challenge patches
were applied to previously untreated test sites on the back. After 24
hours, the patches were removed and the test sites were evaluated for
dermal reactions. The test sites were re-evaluated at 48 and 72 hours.
No skin reaction was observed in any subjects.
Under the study conditions, Gem Seal
25 did not demonstrate a potential for eliciting dermal irritation or
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