Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-084-5
CAS number: 64741-82-8
A complex combination of hydrocarbons from the distillation of the products from a thermal cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C10 through C22 and boiling in the range of approximately 160°C to 370°C (320°F to 698°F).
In a developmental toxicity study,
presumed-pregnant Sprague-Dawley females (12/dose, 15 in sham control
group) were dermally exposed to light coker gas oil for six hour of
exposure at dose levels of 1, 50, or 250 mg/kg/day once daily at seven
days before gestation through day 20 of gestation.
Maternal toxicity included dermal irritation
at doses of 1, 50, and 250 mg/kg; increased absolute and relative food
consumption at 50 mg/kg; decreased body weight, absolute food
consumption during premating, increased relative food consumption during
gestation, and increased absolute amd relative food consumption during
lactation at 250 mg/kg. Decreased pup body weight on lactation days 0
and 4 in the 250 mg/kg dose group. Under conditions of the study, the
NOEL for maternal toxicity is 1 mg/kg/day and for developmental toxicity
the NOEL is 50 mg/kg/day.
This study received a Klimisch score of 2
and is classified as reliable with restrictions because it is a
well-documented study report that follows basic scientific principles.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again