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EC number: 203-227-5
CAS number: 104-68-7
Hematology and serum enzyme examinations
revealed no treatment-related changes. Clinical chemistry investigations
showed decreased concentrations in total bilirubin, total protein,
albumin and globulin as well as increased triglyceride values in the
serum of the high dose animals (1,000 mg/kg bw/day). Similar effects on
clinical chemistry parameters, with somewhat lower severity, were noted
in the mid dose animals (300 mg/kg bw/day). All of these findings were
rather related to adaptive metabolic changes, than indicative of
particular organ toxicity. Although these effects were likely to be
caused by the test material, they were not considered as adverse per se.
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