Registration Dossier
Registration Dossier
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EC number: 203-227-5 | CAS number: 104-68-7
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
For the ecotoxicological studies:
Persistence assessment: The test substance does not meet the criteria of P or vP because it is readily biodegradable. In a standard biodegradation screening test based on OECD guideline 301F, biodegradation of Di-EPh was observed. The extent of DiEPh biodegradation based on BOD, CO2evolution, and DOC removal reached 100.5 ± 1.1%, 87.0 ± 0.3%, and 95.3 ± 0.6%, (mean ± 1 SD), respectively, at the end of the 28-day test. Thus, the biodegradation of DiEPh achieved both the pass level and 10-day window criteria for classification as readily biodegradable in the Manometric Respirometry Test.
Bioaccumulation assessment: The test substance does not meet the criteria of B and vB. The substance has a low potential to bioaccumulate because of its low log Pow value (0.8). Screening criteria for bioaccumulation states that test substances with log Pow values ≤ 4.5 are not B and not vB.
Toxicity Assessment: The 96-hour LC50 for fathead minnow (Pimephales promelas) was 432 mg/L.
The 48-hour EC50 for freshwater invertebrate (Daphnia magna) was 906 mg/L. The 72-hour ErC50 (based on growth rate) for freshwater algae (Pseudokirchnerella subcapitata) was determined to be 393 mg/L. Because these aquatic toxicity endpoints are more than 3000-fold higher than the 0.1 mg/L threshold for toxicity (T), the test substance is not T.
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